DL-Phenylalanine: Benefits And Side Effects

DL-Phenylalanine is an amino acid that is from phenylalanine. Let us look at dl phenylalanine’s benefits and side effects.


Amino acids are the building block of proteins and they play a vital role in the body. Phenylalanine is one of the amino acids that can be seen in foods that your body can use in the production of proteins. It is known to be effective in the treatment of depression, skin disorders, and pain. In this article, we will learn what dl- phenylalanine is, how it can benefit you, and possible health risks.

Phenylalanine exists in two arrangements which are L-phenylalanine and D-phenylalanine. They seem identical but their molecule structure is quite different. The L-phenylalanine can be gotten from foods and they are used in the production of proteins needed in the body. 

D-phenylalanine is metabolized for medical uses. Your body cannot produce L-phenylalanine, so you can get it from your diet. Phenylalanine is also important in the production of some vital molecules in the body. Phenylalanine should be avoided by those who have a genetic disorder known as phenylketonuria. Here we will talk about DL-Phenylalanine benefits and side effects.

What is DL-Phenylalanine?

DL-Phenylalanine is a mixture of L-phenylalanine and D-phenylalanine. L-phenylalanine is the one that is active in your body. It helps in building proteins, vital molecules, and neurotransmitters. L-phenylalanine is an essential amino acid which means your body cannot produce it instead you need to get them to form your diet. Such food is dairy, eggs, nuts, soy, pumpkin seeds, seafood, squash seeds milk, and meat. 

D-phenylalanine is made in the lab unlike L-phenylalanine and they cannot be used by the body as a building block of proteins. It has some amazing health benefits. L-phenylalanine helps in building neurotransmitters like noradrenaline and dopamine which can help maintain your heart rate, control your mood, and some other important functions in your body.

It is a supplement that is good for skin pigmentation and depression. Some studies also show that it is also effective for attention disorders and weight loss. The conversion of one-third of D-phenylalanine produces L-phenylalanine in the body and the remaining is left for some other vital use. Taking D-phenylalanine supplements can help in the reduction of inflammation, production of natural opioids, and enkephalins.

Some studies also show that it can be used for alleviating chronic pain, substance dependence, and mental disorders. DLPhenylalanine has some amazing benefits with not so many side effects.

DL-Phenylalanine Benefits

1. Aids depression

The brain uses the L form of phenylalanine to produce neurotransmitters that boost your mood like noradrenaline and dopamine. If your brain does not have enough dopamine or noradrenaline you tend to start having depression symptoms. Taking 75 to 200 mg of DL-Phenylalanine for 20 days can help reduce depression symptoms. Some doctors can prescribe 50 to 200 mg of DLPhenylalanine for two to four weeks. 

2. Substance dependence

The opioids inside your body do not attack pain signals directly, they go into the brain and regulate some chemicals in there to make you have a good mood. For those having to struggle with opioids withdrawal, taking D-phenylalanine can help make your mood better. People having issues with alcohol withdrawal can also take D-phenylalanine supplements to alleviate withdrawal symptoms. An increase in the level of enkephalins and dopamine can help a patient that is struggling with alcohol withdrawal. 

3. Weight loss

DLPhenylalanine supplements can be taken to burn fats in the body. Supplementing on L-phenylalanine can lower your food intake and this will lead to weight loss. Since DLPhenylalanine is an amino acid so it is believed that it can also work as a weight-loss supplement.

4. Pain management

The D-phenylalanine and DLPhenylalanine can help increase the level of internal opioids in your body. A high dose of dl- phenylalanine which is 1,500 to 3,000 mg daily can help in pain management. The antidepressant effect of D-phenylalanine is linked to its effect as a painkiller. 

5. Attention disorders

If your brain is low on dopamine, you tend to suffer from ADHD. Phenylalanine can help in the production of dopamine for those with ADHD also known as attention deficit disorder. Even though there is not enough research to prove that phenylalanine is effective for attention deficit disorder, it can still be used to increase the level of dopamine which can alleviate the symptoms of attention deficit disorder. Daily intake of 150 to 1,200 mg of DL-Phenylalanine for two weeks can help in patients with attention deficit disorder.

Side effects of DLPhenylalanine

A lot of food rich in protein contains DLPhenylalanine. In general, they are considered. The level of amino acid found in DLPhenylalanine cannot be dangerous to your health. Pregnant women must avoid supplementing on phenylalanine.

There is a genetic disorder known as phenylketonuria; those with this disorder cannot properly digest phenylalanine. This entails that those with this disorder should avoid taking food too high in DLPhenylalanine and they should never try taking DLPhenylalanine supplements. If a patient with PKU takes DLPhenylalanine supplements or food rich in DLPhenylalanine, it can help lead to a high level of phenylalanine in the blood of the person, and a high level of phenylalanine in the blood can lead to intellectual disability and brain damage. In some people, it can interfere with the amino acids in your brain. 

This disorder is so fatal that babies are screened at birth to determine if he or she has PKU. Those with PKU are required to eat food low in protein and it is lifetime management. Pregnant women and children mustn’t attempt to take DLPhenylalanine supplements. Some people do take DLPhenylalanine supplements to boost their mood, some use it for mild pain. It can still cause some side effects in a few users like headache, nausea, and irritability.

Drug interactions can be fatal that is why before taking DLPhenylalanine supplements consult your doctor to be sure that it is safe for you to take these supplements with the medications you are taking. DLPhenylalanine should not be taken with Parkinson’s disease medication because phenylalanine can block the transport of the medication to the brain and this makes the medication less potent which will worsen the condition of the patient. 

DLPhenylalanine benefits and side effects have been listed above, so now you know if you should buy supplements containing DLPhenylalanine or not. If you have PKU do not attempt to take DLPhenylalanine supplements and try as much as possible to stick to your low protein diet.

Leave a Reply

Your email address will not be published. Required fields are marked *